Cognition, mood & sleepNasal spray

Selank

Also known as: Tuftsin analogue · TP-7

Selank is a synthetic peptide based on the immune-signalling molecule tuftsin, studied for stress resilience, calm and focus without sedation.

Physician-reviewedDr. Bushra Mir, Medical Director · DHA-licensedReviewed

The molecule, up close

H₂NONHONHOOHHNNNH₂GHK · glycyl-L-histidyl-L-lysine
Class
Synthetic peptide (tuftsin analogue)
Origin
Developed in Russia from the immune peptide tuftsin
Chemistry
Heptapeptide, modified for stability
Typical format
Nasal spray
Regulatory status
Approved in some countries; under study elsewhere

This page is educational information, not medical advice or an offer of treatment. Peptides used clinically are prescription medicines; whether any is appropriate for you is a decision a physician makes after a diagnostic assessment.

What it is

Selank was developed in Russia as a stable analogue of tuftsin, a small immune-signalling peptide. It has been studied there in the context of anxiety and stress, and is one of the better-known "nootropic" peptides in the wider conversation.

Its distinctive angle in research is an interest in calm and focus without the sedation associated with some conventional options — a framing best held alongside the limits of the evidence outside its country of origin.

What it's studied for

Interest centres on anxiety-related signalling, stress resilience and attention. It's studied as a peptide that might support these without heavy sedative effects.

Anxiety and stress are well-understood clinically, so a physician weighs Selank alongside the established options as part of a proper assessment rather than treating it as an automatic first choice.

The science

Research explores effects on neurotransmitter systems — including GABA and serotonin-related pathways — and on brain-derived signalling molecules that support nerve cells.

The mechanism isn't fully mapped, and much of the detailed work sits outside large international trials.

SelankNASAL SPRAY

Typical form

Nasal spray

Shown in the dispensing format most often used in research and clinical settings. Where any protocol is appropriate, the route, dose and schedule are a physician’s decision — not a fixed recipe.

Safety & considerations

Prescription-only, physician-supervised and individualised where used. A proper assessment of anxiety and stress comes first — there's effective, evidence-based care to weigh alongside it, and a physician helps place Selank in that fuller picture.

As with any peptide used outside its approved settings, product quality and clinical oversight are central to using it responsibly.

Status & oversight

Selank is approved and used in some countries; elsewhere it's still under study. Any clinical use is a physician's decision after assessment, and it sits alongside — not in place of — established mental-health care.

Common questions

Selank, in brief.

What is Selank used for?
It's studied for stress resilience, calm and focus. In some countries it's used clinically; elsewhere it's still under study. Either way, underlying causes of anxiety are worth assessing with a clinician first.
Is Selank like an anti-anxiety medication?
It's studied in a similar area but isn't an established, widely approved anti-anxiety medicine, and shouldn't be treated as a substitute for evidence-based mental-health care.
Does Selank cause drowsiness?
Part of the research interest is that it's studied as a calming peptide without heavy sedation, but individual responses vary and the evidence is limited. Any use is supervised and individual.

Peptides of this kind are prescription medicines. Whether any protocol is appropriate is decided the way the rest of the practice works — from data, after an assessment.

How this is written

Physician-reviewed and evidence-led. We describe what a compound is studied for and where the evidence stands — not what it will do for you — and we revise pages as the science changes. Reviewed by Dr. Bushra Mir, Medical Director · DHA-licensed.

References

Peer-reviewed references for this compound are added by the physician author before publication.